Biomarker and Bioanalytical Solutions To De-Risk and Advance Your Therapeutic Pipeline

Reduce clinical trial risk by validating your therapeutic’s biology in human disease models. We generate mechanistic data from fresh patient samples that predicts clinical response, guides biomarker strategy, and strengthens regulatory submissions before you enter the clinic.

Your biomarker strategy determines what data you collect and what regulatory questions you can answer. We develop custom biomarker panels that measure what matters: target engagement, pathway modulation, disease activity, and the clinical signals that drive development decisions from Phase I through approval.

Accelerate your bioanalysis with precise LC‑MS/MS quantification of small molecules, peptides, proteins, and ADCs. Our dedicated 16,500 sq ft UK facility delivers rapid, ICH M10‑validated PK, TK, and biomarker analysis from discovery through clinical development, with the GLP/GCP compliance and turnaround speed your programmes require.

Developing large‑molecule biotherapeutics requires sensitive, validated immunoassays you can trust. We design bespoke ligand‑binding assays for PK, ADA, and biomarker quantification, delivering the precision and GCP/GLP compliance needed for confident regulatory decision‑making.

From immunophenotyping rare cells to measuring target engagement and immune function, our custom flow cytometry panels deliver validated, high‑parameter analysis. Designed to CLSI H62 standards and tailored to your endpoints, our assays provide the reproducible cellular insights that guide therapeutic development decisions.

Measure antigen‑specific immune responses at single‑cell resolution. Our GCLP‑compliant ELISpot assays detect low‑frequency T‑cell and B‑cell responses critical for vaccine development, immunotherapy monitoring, and CAR‑T assessment. From custom assay design to data analysis, we deliver the sensitive, validated cytokine detection your immune monitoring trials depend on.

GLP toxicology studies require verified dose formulation concentrations. Our Manchester facility verifies formulation accuracy and stability, ensuring regulatory submissions meet requirements. We validate concentration, consistency, and shelf‑life using proven analytical methods.